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Keywords hantaan virus;prokaryotic expression;fusion protein; 汉滩病毒;原核表达;融合蛋白;
Keywords Hantaan virus;chimeric antibody;transgenic plants;plantibody; 汉滩病毒;嵌合抗体;转基因植物;植物抗体;
Keywords Hantaan virus;nucleocapsid protein;multipeptide antigen;eukaryotic expression; 汉滩病毒;核衣壳蛋白;多肽抗原;真核表达;
Keywords Hantaan virus;Phage display peptide library;Neutralizing antibody;Epitope; 关键词汉滩病毒;噬菌体展示肽文库;中和抗体;表位;
Keywords hantaan virus;eukaryotic expression;genetic immunization;nucleocapsid protein;prokanotic expression;S gene; 汉滩病毒;S基因;核蛋白;原核表达;真核表达;基因免疫;
Keywords Hantaan virus（HTNV）;nucleocapsid protein（NP） epitope;expression;antigenicity immunogenicity;protective cell-mediated immune response; 汉滩病毒;核衣壳蛋白;抗原表位;基因定位;原核表达;抗原性;免疫原性;保护性细胞免疫反应;
Keywords Hantaan virus （HTNV）;Recombinant vaccinia virus（rVV）;Hemorrhagic Fever with Renal Syndrome （HFRS）;EB virus（EBV）;B lymphoblastoid cell lines （B-LCL）; 汉滩病毒;重组痘苗病毒;肾综合征出血热;EB病毒;B淋巴母细胞系;
The important agent of this disease is Hantaan Virus. 汉滩病毒。
The rat lung and kidney were taken to examine the epidemic hemorrhagic fever antigen, isolate hantaan virus, and culture Leptospira interrogans. 取鼠肺和鼠肾分别检验流行性出血热抗原及分离病毒和分离培养钩端螺旋体。
While preventing and controlling the HFRS of Hantaan virus, the Seoul virus infection should also be considered at the same time. 应考虑同时预防和控制姬鼠型和家鼠型病例发生。
Schmaljohn CS,Chu YK,Schmaljohn AL,et al.Antigenic subunits of hantaan virus expressed by baculovirus and vaccinia virus recombinants[J].J Virol,1990,64:3162. 尹文;徐志凯;阎岩;等.;汉坦病毒S基因的分段表达及表达产物的鉴定[J]
Keywords gasmid mite;chigger mite;Hantaan virus; 关键词革螨;恙螨;汉坦病毒;
Four of the hantavirus species, Hantaan virus(HTNV), Seoul virus(SEOV), Dobrava/Belgrade virus(DOBV), and Puumala virus(PUUV), which are all different serotypes, are known to cause HFRS,while Sin Nombre virus(SNV) causes HPS. 已知致病的汉坦病毒(Hantavirus，HV)主要有5种型别，包括汉滩病毒(HTNV)、汉城病毒(SEOV)、多布拉伐病毒(DOBV)、普马拉病毒(PUUV)和辛诺柏病毒(SNV)。我国目前流行的汉坦病毒为前两型，即HTN型和SEO型。
The method of clone and expression of the SEO virus antigen from NP and NP type specific region coding gene was established,and made simple and reliable measurement method of SEO serotype in Hantaan virus possible. 建立了SEO型病毒全NP蛋白及NP蛋白型特异区编码基因的克隆和表达方法 ,为开发简便、可靠的SEO型血清学分型检验方法奠定了基础。
C57BL/6 mice were immunized intramuscularly every 2 weeks for 3 times with pcDNA3.0-backbone recombinant plasmids of Hantaan virus 84Fli that encoded the NP and GP proteins,and contrasted with bivalent inactivated EHF vaccine. 为了加强我国病毒性出血热的防治;本研究将汉滩病毒84Fli株核蛋白S和糖蛋白M编码片段分别克隆至pcDNA3.;0载体;构建了pcDNA3/84S和pcDNA3/84M重组质粒;等量混合采用肌肉注射途径免疫C57BL/6小鼠;免疫3次;每次间隔2周;同时与双价出血热病毒灭活疫苗进行对比。
Sheshberadaran H,et al.Antigenic relationship between hantaan viruses analysed by immunoprecipitation.J Gen Virol,1988,69:2645. 梁米芳，等.;汉坦病毒S基因在大肠杆菌中的表达及其初步应用
Keywords ScFv;Diabody;Hantaan virus;Baculovirus;Insect cell; 单链抗体;双链抗体;汉滩病毒;杆状病毒;昆虫细胞;
Hantaan virus Nucleocapsid protein 汉滩病毒核蛋白
Keywords bifidobacterial peptidoglycan;hantaan virus nucleoprotein;adjuvant; 关键词双歧杆菌;肽聚糖;汉坦病毒核蛋白;佐剂;
Keywords Construction and panning;Hantaan virus M fragment;Phage library; 关键词构建及筛选;汉滩病毒M片段;噬菌体文库;